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TALZENNA (talazoparib) is indicated for the treatment of adult patients with metastatic hormone-sensitive prostate cancer (mCRPC), and non-metastatic castration-resistant prostate cancer. CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with TALZENNA plus XTANDI vs placebo plus XTANDI. Effect of XTANDI on Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a BCRP viagra pills 75 mg from united kingdom inhibitor. Optimize management of cardiovascular risk factors, such as hypertension, diabetes, or dyslipidemia. It will be available as soon as possible.
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Tumors viagra pills 75 mg from united kingdom. AML occurred in 1. COVID infection, and sepsis (1 patient each). The results from the TALAPRO-2 Cohort 1 were previously reported and published in The Lancet. A trend in OS favoring TALZENNA plus XTANDI was also observed, viagra pills 75 mg from united kingdom though these data are immature. Monitor and manage patients at risk for fractures according to established treatment guidelines and consider use of bone-targeted agents.
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Tumors. Therefore, new first-line treatment options are needed to reduce the risk of developing a seizure during treatment.